XPH State Street SPDR S&P Pharmaceuticals ETF
SPDR Series Trust - SPDR S&P Pharmaceuticals ETF is an exchange traded fund launched by State Street Global Advisors, Inc. It is managed by SSGA Funds Management, Inc. It invests in public equity markets of the United States. The fund invests in stocks of companies operating across health care, pharmaceuticals, biotechnology and life sciences sectors. The fund invests in growth and value stocks of companies across diversified market capitalization. It seeks to track the performance of the S&P Pharmaceuticals Select Industry Index, by using representative sampling technique. SPDR Series Trust - SPDR S&P Pharmaceuticals ETF was formed on June 16, 2006 and is domiciled in the United States.
Performance
| 1M | 3M | YTD | 1Y | 3Y ann. | 5Y ann. | |
|---|---|---|---|---|---|---|
| XPH | +6.4% | -5.6% | +18.0% | +31.6% | +23.4% | +5.8% |
| Equity average (4725 funds) | -2.2% | -4.7% | +3008.3% | +1886.0% | +15.1% | +2.6% |
Insider activity in the holdings
Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$365K net.
| Holding | Weight | Insiders bought | Insiders sold |
|---|---|---|---|
| RAPP RAPPORT THERAPEUTICS INC | 1.13% | $22.0M | $4.5M |
| ALMS ALUMIS INC | 1.34% | $10.7M | $1.0M |
| RLMD RELMADA THERAPEUTICS INC | 1.11% | $1.7M | $0 |
| ELAN ELANCO ANIMAL HEALTH INC | 2.23% | $1.0M | $100K |
| AQST AQUESTIVE THERAPEUTICS INC | 0.89% | $99K | $379K |
| EYPT EYEPOINT INC | 0.08% | $52K | $0 |
| LXRX LEXICON PHARMACEUTICALS INC | 0.81% | $50K | $0 |
Holdings · as of Nov 12, 2026
| # | Holding | Weight |
|---|---|---|
| 1 | XERS XERIS BIOPHARMA HOLDINGS INC | 4.24% |
| 2 | MANE VERADERMICS INC | 3.11% |
| 3 | MAZE MAZE THERAPEUTICS INC | 2.63% |
| 4 | LLY ELI LILLY + CO | 2.53% |
| 5 | VTRS VIATRIS INC | 2.53% |
| 6 | PCRX PACIRA BIOSCIENCES INC | 2.52% |
| 7 | AMRX AMNEAL PHARMACEUTICALS INC | 2.49% |
| 8 | SEPN SEPTERNA INC | 2.37% |
| 9 | ETON ETON PHARMACEUTICALS INC | 2.30% |
| 10 | RPRX ROYALTY PHARMA PLC CL A | 2.29% |
| 11 | PRGO PERRIGO CO PLC | 2.29% |
| 12 | ZTS ZOETIS INC | 2.23% |
| 13 | ELAN ELANCO ANIMAL HEALTH INC | 2.23% |
| 14 | LGND LIGAND PHARMACEUTICALS | 2.18% |
| 15 | EWTX EDGEWISE THERAPEUTICS INC | 2.17% |
| 16 | PFE PFIZER INC | 2.10% |
| 17 | JNJ JOHNSON + JOHNSON | 2.08% |
| 18 | COLL COLLEGIUM PHARMACEUTICAL INC | 2.05% |
| 19 | JAZZ JAZZ PHARMACEUTICALS PLC | 2.04% |
| 20 | OGN ORGANON + CO | 2.01% |
| 21 | ANIP ANI PHARMACEUTICALS INC | 1.99% |
| 22 | MRK MERCK + CO. INC. | 1.98% |
| 23 | AMLX AMYLYX PHARMACEUTICALS INC | 1.94% |
| 24 | BMY BRISTOL MYERS SQUIBB CO | 1.93% |
| 25 | OMER OMEROS CORP | 1.85% |
| 26 | TARS TARSUS PHARMACEUTICALS INC | 1.84% |
| 27 | MBX MBX BIOSCIENCES INC | 1.82% |
| 28 | DFTX DEFINIUM THERAPEUTICS INC | 1.80% |
| 29 | PBH PRESTIGE CONSUMER HEALTHCARE | 1.80% |
| 30 | INVA INNOVIVA INC | 1.77% |
| 31 | ELVN ENLIVEN THERAPEUTICS INC | 1.76% |
| 32 | TRVI TREVI THERAPEUTICS INC | 1.76% |
| 33 | AMPH AMPHASTAR PHARMACEUTICALS IN | 1.71% |
| 34 | SUPN SUPERNUS INC | 1.68% |
| 35 | ZVRA ZEVRA THERAPEUTICS INC | 1.66% |
| 36 | HRMY HARMONY BIOSCIENCES HOLDINGS | 1.63% |
| 37 | LBRX LB PHARMACEUTICALS INC | 1.60% |
| 38 | LQDA LIQUIDIA CORP | 1.58% |
| 39 | HROW HARROW INC | 1.55% |
| 40 | ANRO ALTO NEUROSCIENCE INC | 1.50% |
| 41 | AXSM AXSOME THERAPEUTICS INC | 1.40% |
| 42 | ALMS ALUMIS INC | 1.34% |
| 43 | NUVB NUVATION BIO INC | 1.30% |
| 44 | CORT CORCEPT THERAPEUTICS INC | 1.28% |
| 45 | WVE WAVE LIFE SCIENCES INC | 1.26% |
| 46 | OCUL OCULAR THERAPEUTIX INC | 1.15% |
| 47 | PAHC PHIBRO ANIMAL HEALTH CORP A | 1.15% |
| 48 | RAPP RAPPORT THERAPEUTICS INC | 1.13% |
| 49 | RLMD RELMADA THERAPEUTICS INC | 1.11% |
| 50 | PHAT PHATHOM PHARMACEUTICALS INC | 0.97% |
| 51 | ACRS ACLARIS THERAPEUTICS INC | 0.95% |
| 52 | AVLN AVALYN PHARMA INC | 0.94% |
| 53 | AQST AQUESTIVE THERAPEUTICS INC | 0.89% |
| 54 | CRMD CORMEDIX INC | 0.86% |
| 55 | LXRX LEXICON PHARMACEUTICALS INC | 0.81% |
| 56 | ARVN ARVINAS INC | 0.67% |
| 57 | EOLS EVOLUS INC | 0.67% |
| 58 | BIOA BIOAGE LABS INC | 0.57% |
| 59 | CTNM CONTINEUM THERAPEUTICS INC A | 0.52% |
| 60 | EYPT EYEPOINT INC | 0.08% |
| 61 | XPH CONTRA ESPERION THERAP | 0.01% |
Sector breakdown
Country breakdown
Distributions
| Date | Per unit |
|---|---|
| Sep 21, 2026 | $0.0416 |
| Jun 22, 2026 | $0.0590 |
| Mar 23, 2026 | $0.0610 |
| Dec 22, 2025 | $0.1130 |
| Sep 22, 2025 | $0.1026 |
| Jun 23, 2025 | $0.0959 |
| Mar 24, 2025 | $0.1533 |
| Dec 23, 2024 | $0.1548 |
| Sep 23, 2024 | $0.1947 |
| Jun 24, 2024 | $0.1557 |
| Mar 18, 2024 | $0.1730 |
| Dec 18, 2023 | $0.1744 |
| Sep 18, 2023 | $0.1201 |
| Jun 20, 2023 | $0.1235 |
| Mar 20, 2023 | $0.1154 |
| Dec 19, 2022 | $0.1940 |
| Sep 19, 2022 | $0.1320 |
| Jun 21, 2022 | $0.1645 |
| Mar 21, 2022 | $0.1811 |
| Dec 20, 2021 | $0.1938 |
| Sep 20, 2021 | $0.0892 |
| Jun 21, 2021 | $0.0836 |
| Mar 22, 2021 | $0.0730 |
| Dec 21, 2020 | $0.0538 |
| Sep 21, 2020 | $0.0523 |
| Jun 22, 2020 | $0.0667 |
| Mar 23, 2020 | $0.0717 |
| Dec 23, 2019 | $0.0711 |
| Sep 23, 2019 | $0.0840 |
| Jun 24, 2019 | $0.0683 |
| Mar 18, 2019 | $0.0678 |
| Dec 24, 2018 | $0.1057 |
| Sep 24, 2018 | $0.0547 |
| Jun 15, 2018 | $0.0588 |
| Mar 16, 2018 | $0.0194 |
| Dec 15, 2017 | $0.1080 |
| Sep 15, 2017 | $0.0723 |
| Jun 16, 2017 | $0.0850 |
| Mar 17, 2017 | $0.0270 |
| Dec 16, 2016 | $0.0910 |
Members of Congress who disclosed this ETF
No member of Congress has disclosed a trade in XPH in the filings we hold.
Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error