SpaceX~$1TSpaceX~$1T
Insider Buying
Subscribe

← ETF Screener

PBE Invesco Biotechnology & Genome ETF

Issuer
Invesco
Inception
Jun 23, 2005
AUM
$435.8M
Expense ratio
0.59%
Yield
1.37%
Asset class
Equity
Holdings
31
Last price
$97.33

The Invesco Biotechnology & Genome ETF (PBE) seeks to replicate the performance of the Dynamic Biotech & Genome Intellidex Index. This fund typically allocates a minimum of 90% of its total assets to the securities comprising the underlying index. The Index is constructed to achieve capital appreciation by thoroughly evaluating companies based on several investment criteria, including their price momentum, earnings growth, overall quality, management decisions, and valuation. It consists of 30 U.S.-based companies within the biotechnology and genome sectors. These companies are primarily involved in the research, development, manufacture, and distribution of various biotechnological products, services, and processes, or they are businesses that stand to gain significantly from scientific and technological breakthroughs in biotechnology and genetic engineering. Both the ETF and its benchmark index undergo quarterly rebalancing and reconstitution in February, May, August, and November.

+25.5%
2025-11-13low 75.60 · high 104.672026-11-13

Performance

1M3MYTD1Y3Y ann.5Y ann.
PBE+0.7%+3.9%+19.8%+27.4%+21.3%+6.6%
Equity average (4725 funds)-2.2%-4.7%+3008.3%+1886.0%+15.1%+2.6%

Insider activity in the holdings

Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$0 net.

No open-market insider buys in the holdings in the last 90 days.

Holdings · as of Nov 12, 2026

#HoldingWeight
1REGN Regeneron Pharmaceuticals Inc5.66%
2BIIB Biogen Inc5.64%
3GILD Gilead Sciences Inc5.61%
4RPRX Royalty Pharma PLC5.55%
5AMGN Amgen Inc5.20%
6VRTX Vertex Pharmaceuticals Inc4.86%
7NTRA Natera Inc4.67%
8ILMN Illumina Inc4.65%
9MRNA Moderna Inc4.20%
10VCEL Vericel Corp3.69%
11EXEL Exelixis Inc3.34%
12TGTX TG Therapeutics Inc3.18%
13QGEN QIAGEN NV3.09%
14UTHR United Therapeutics Corp3.08%
15NBIX Neurocrine Biosciences Inc3.05%
16NVAX Novavax Inc2.84%
17RGEN Repligen Corp2.55%
18INCY Incyte Corp2.53%
19HALO Halozyme Therapeutics Inc2.49%
20LEGN Legend Biotech Corp2.46%
21COLL Collegium Pharmaceutical Inc2.42%
22PTGX Protagonist Therapeutics Inc2.40%
23PTCT PTC Therapeutics Inc2.37%
24BMRN BioMarin Pharmaceutical Inc2.37%
25SRPT Sarepta Therapeutics Inc2.36%
26ANAB AnaptysBio Inc2.24%
27ARDX Ardelyx Inc2.22%
28BCRX BioCryst Pharmaceuticals Inc2.09%
29ACAD ACADIA Pharmaceuticals Inc1.61%
30VCYT Veracyte Inc1.53%
31AGPXX Invesco Government & Agency Portfolio0.04%
32PBE CASH & EQUIVALENTS0.00%

Sector breakdown

Healthcare100.0%

Country breakdown

United States100.0%

Distributions

DatePer unit
Sep 21, 2026$0.0187
Jun 22, 2026$0.8106
Mar 23, 2026$0.0824
Dec 22, 2025$0.4197
Sep 22, 2025$0.2341
Jun 23, 2025$0.1305
Mar 24, 2025$0.0341
Jun 24, 2024$0.0082
Mar 18, 2024$0.0242
Jun 20, 2023$0.0141
Mar 23, 2020$0.0290
Sep 24, 2018$0.0021
Jun 16, 2017$0.2153
Mar 17, 2017$0.0555
Dec 16, 2016$0.1208
Sep 16, 2016$0.0283
Dec 18, 2015$0.3082
Sep 18, 2015$0.1366
Jun 19, 2015$0.1227
Sep 19, 2014$0.0429
Jun 20, 2014$0.2340
Dec 18, 2009$0.0755

Members of Congress who disclosed this ETF

No member of Congress has disclosed a trade in PBE in the filings we hold.

Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error