IBBQ Invesco Nasdaq Biotechnology ETF
Issuer
Invesco
Inception
Jun 11, 2021
AUM
$127.1M
Expense ratio
0.19%
Yield
1.10%
Asset class
Equity
Holdings
246
Last price
$35.44
The Invesco Nasdaq Biotechnology ETF (IBBQ) seeks to mirror the investment performance of the Nasdaq Biotechnology Index. To achieve this, the Fund generally dedicates at least 90% of its total capital to the securities that make up this benchmark index. The underlying Index itself is specifically designed to gauge the returns of biotechnology and pharmaceutical companies whose shares are publicly traded on the Nasdaq Stock Market. Both the ETF and its corresponding Index undergo a yearly review and update of their composition each December, and their weightings are adjusted quarterly in March, June, September, and December.
+28.9%
2025-11-13low 27.46 · high 36.872026-11-13
Performance
| 1M | 3M | YTD | 1Y | 3Y ann. | 5Y ann. | |
|---|---|---|---|---|---|---|
| IBBQ | +4.5% | +5.6% | +26.0% | +30.4% | +24.6% | +8.9% |
| Equity average (4725 funds) | -2.2% | -4.7% | +3008.3% | +1886.0% | +15.1% | +2.6% |
Insider activity in the holdings
Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$1.0M net.
| Holding | Weight | Insiders bought | Insiders sold |
|---|---|---|---|
| KOD Kodiak Sciences Inc | 0.43% | $181.3M | $2.7M |
| LYEL Lyell Immunopharma Inc | 0.02% | $50.0M | $216K |
| MDGL Madrigal Pharmaceuticals Inc | 0.63% | $35.0M | $7.0M |
| RAPP Rapport Therapeutics Inc | 0.08% | $22.0M | $4.5M |
| SRRK Scholar Rock Holding Corp | 0.36% | $12.0M | $0 |
| ALMS Alumis Inc | 0.05% | $10.7M | $1.0M |
| PRTA Prothena Corp PLC | 0.03% | $9.8M | $0 |
| INBX Inhibrx Biosciences Inc | 0.08% | $6.3M | $279K |
| OBIO Orchestra BioMed Holdings Inc | 0.02% | $6.3M | $256K |
| KURA Kura Oncology Inc | 0.04% | $2.4M | $1.7M |
| XENE Xenon Pharmaceuticals Inc | 0.26% | $1.7M | $426K |
| ABCL AbCellera Biologics Inc | 0.24% | $1.4M | $0 |
| RGNX REGENXBIO Inc | 0.04% | $949K | $0 |
| ALNY Alnylam Pharmaceuticals Inc | 1.35% | $543K | $399K |
| LRMR Larimar Therapeutics Inc | 0.02% | $382K | $0 |
Holdings · as of Nov 12, 2026
| # | Holding | Weight |
|---|---|---|
| 1 | GILD Gilead Sciences Inc | 8.91% |
| 2 | AMGN Amgen Inc | 8.37% |
| 3 | VRTX Vertex Pharmaceuticals Inc | 7.72% |
| 4 | MRNA Moderna Inc | 6.24% |
| 5 | REGN Regeneron Pharmaceuticals Inc | 6.10% |
| 6 | RVMD Revolution Medicines Inc | 2.44% |
| 7 | BIIB Biogen Inc | 2.35% |
| 8 | ILMN Illumina Inc | 2.02% |
| 9 | RPRX Royalty Pharma PLC | 1.96% |
| 10 | ROIV Roivant Sciences Ltd | 1.90% |
| 11 | ARGX Argenx SE | 1.67% |
| 12 | INSM Insmed Inc | 1.66% |
| 13 | UTHR United Therapeutics Corp | 1.61% |
| 14 | INCY Incyte Corp | 1.56% |
| 15 | VTRS Viatris Inc | 1.52% |
| 16 | ALNY Alnylam Pharmaceuticals Inc | 1.35% |
| 17 | GH Guardant Health Inc | 1.31% |
| 18 | MEDP Medpace Holdings Inc | 1.16% |
| 19 | NBIX Neurocrine Biosciences Inc | 1.11% |
| 20 | EXEL Exelixis Inc | 1.10% |
| 21 | JAZZ Jazz Pharmaceuticals PLC | 1.01% |
| 22 | BBIO Bridgebio Pharma Inc | 1.00% |
| 23 | ASND Ascendis Pharma A/S | 1.00% |
| 24 | ONC BeOne Medicines Ltd | 0.95% |
| 25 | TEM Tempus AI Inc | 0.87% |
| 26 | SMMT Summit Therapeutics Inc | 0.83% |
| 27 | HALO Halozyme Therapeutics Inc | 0.72% |
| 28 | BMRN BioMarin Pharmaceutical Inc | 0.71% |
| 29 | KYMR Kymera Therapeutics Inc | 0.70% |
| 30 | SNY Sanofi SA | 0.66% |
| 31 | PCVX Vaxcyte Inc | 0.64% |
| 32 | BNTX BioNTech SE | 0.64% |
| 33 | MDGL Madrigal Pharmaceuticals Inc | 0.63% |
| 34 | PRAX Praxis Precision Medicines Inc | 0.61% |
| 35 | SYRE Spyre Therapeutics Inc | 0.59% |
| 36 | KRYS Krystal Biotech Inc | 0.58% |
| 37 | PTGX Protagonist Therapeutics Inc | 0.55% |
| 38 | CYTK Cytokinetics Inc | 0.51% |
| 39 | TWST Twist Bioscience Corp | 0.51% |
| 40 | ALKS Alkermes PLC | 0.51% |
| 41 | AXSM Axsome Therapeutics Inc | 0.49% |
| 42 | RYTM Rhythm Pharmaceuticals Inc | 0.49% |
| 43 | IMVT Immunovant Inc | 0.48% |
| 44 | AMRX Amneal Pharmaceuticals Inc | 0.47% |
| 45 | TXG 10X Genomics Inc | 0.47% |
| 46 | ORKA Oruka Therapeutics Inc | 0.44% |
| 47 | IBRX ImmunityBio Inc | 0.44% |
| 48 | ARWR Arrowhead Pharmaceuticals Inc | 0.44% |
| 49 | CAI Caris Life Sciences Inc | 0.43% |
| 50 | KOD Kodiak Sciences Inc | 0.43% |
| 51 | CGON CG Oncology Inc | 0.40% |
| 52 | LGND Ligand Pharmaceuticals Inc | 0.40% |
| 53 | MIRM Mirum Pharmaceuticals Inc | 0.39% |
| 54 | INDV Supernus Inc | 0.38% |
| 55 | ERAS Erasca Inc | 0.37% |
| 56 | SRRK Scholar Rock Holding Corp | 0.36% |
| 57 | GRAL GRAIL Inc | 0.35% |
| 58 | PTCT PTC Therapeutics Inc | 0.34% |
| 59 | ABVX Abivax SA | 0.33% |
| 60 | GMAB Genmab A/S | 0.33% |
| 61 | EWTX Edgewise Therapeutics Inc | 0.32% |
| 62 | COGT Cogent Biosciences Inc | 0.32% |
| 63 | TVTX Travere Therapeutics Inc | 0.31% |
| 64 | ADPT Adaptive Biotechnologies Corp | 0.30% |
| 65 | IONS Ionis Pharmaceuticals Inc | 0.30% |
| 66 | DFTX Definium Therapeutics Inc | 0.29% |
| 67 | KNSA Kiniksa Pharmaceuticals International Plc | 0.29% |
| 68 | CRSP CRISPR Therapeutics AG | 0.28% |
| 69 | TNGX Tango Therapeutics Inc | 0.27% |
| 70 | RLAY Relay Therapeutics Inc | 0.27% |
| 71 | XENE Xenon Pharmaceuticals Inc | 0.26% |
| 72 | AMLX Amylyx Pharmaceuticals Inc | 0.25% |
| 73 | ABCL AbCellera Biologics Inc | 0.24% |
| 74 | ELVN Enliven Therapeutics Inc | 0.24% |
| 75 | IOVA Iovance Biotherapeutics Inc | 0.23% |
| 76 | ARQT Arcutis Biotherapeutics Inc | 0.22% |
| 77 | TARS Tarsus Pharmaceuticals Inc | 0.22% |
| 78 | DYN Dyne Therapeutics Inc | 0.21% |
| 79 | IRON Disc Medicine Inc | 0.21% |
| 80 | ACAD ACADIA Pharmaceuticals Inc | 0.20% |
| 81 | DNLI Denali Therapeutics Inc | 0.20% |
| 82 | IDYA Ideaya Biosciences Inc | 0.20% |
| 83 | VCEL Vericel Corp | 0.19% |
| 84 | XERS Xeris Biopharma Holdings Inc | 0.19% |
| 85 | ADMA ADMA Biologics Inc | 0.19% |
| 86 | XNCR Xencor Inc | 0.19% |
| 87 | MBX MBX Biosciences Inc | 0.17% |
| 88 | BEAM Beam Therapeutics Inc | 0.17% |
| 89 | NAMS Newamsterdam Pharma Co NV | 0.16% |
| 90 | PHVS Pharvaris NV | 0.15% |
| 91 | SEPN Septerna Inc | 0.14% |
| 92 | VIR Vir Biotechnology Inc | 0.14% |
| 93 | VERA Vera Therapeutics Inc | 0.14% |
| 94 | AUPH Aurinia Pharmaceuticals Inc | 0.14% |
| 95 | TRVI Trevi Therapeutics Inc | 0.13% |
| 96 | REPL Replimune Group Inc | 0.13% |
| 97 | ZYME Zymeworks Inc | 0.13% |
| 98 | MAZE Maze Therapeutics Inc | 0.13% |
| 99 | VCYT Veracyte Inc | 0.13% |
| 100 | HRMY Harmony Biosciences Holdings Inc | 0.12% |
| 101 | AGIO Agios Pharmaceuticals Inc | 0.12% |
| 102 | ETON Eton Pharmaceuticals Inc | 0.12% |
| 103 | BCRX BioCryst Pharmaceuticals Inc | 0.12% |
| 104 | FTRE Fortrea Holdings Inc | 0.12% |
| 105 | RXRX Recursion Pharmaceuticals Inc | 0.12% |
| 106 | ZBIO Zenas Biopharma Inc | 0.12% |
| 107 | AGPXX Invesco Government & Agency Portfolio | 0.12% |
| 108 | LEGN Legend Biotech Corp | 0.11% |
| 109 | STOK Stoke Therapeutics Inc | 0.11% |
| 110 | TRAX First Tracks Biotherapeutics Inc | 0.11% |
| 111 | SRPT Sarepta Therapeutics Inc | 0.11% |
| 112 | ABSI Absci Corp | 0.11% |
| 113 | GPCR Structure Therapeutics Inc | 0.11% |
| 114 | PSNL Personalis Inc | 0.11% |
| 115 | QURE uniQure NV | 0.11% |
| 116 | NRIX Nurix Therapeutics Inc | 0.11% |
| 117 | PGEN Precigen Inc | 0.11% |
| 118 | ALVO Alvotech SA | 0.10% |
| 119 | NVAX Novavax Inc | 0.10% |
| 120 | RARE Ultragenyx Pharmaceutical Inc | 0.10% |
| 121 | ANIP ANI Pharmaceuticals Inc | 0.10% |
| 122 | NTLA Intellia Therapeutics Inc | 0.10% |
| 123 | IMCR Immunocore Holdings PLC | 0.09% |
| 124 | OCUL Ocular Therapeutix Inc | 0.09% |
| 125 | ANAB AnaptysBio Inc | 0.09% |
| 126 | PCRX Pacira BioSciences Inc | 0.09% |
| 127 | MLYS Mineralys Therapeutics Inc | 0.09% |
| 128 | NVCR Novocure Ltd | 0.09% |
| 129 | TSHA Taysha Gene Therapies Inc | 0.09% |
| 130 | INVA Innoviva Inc | 0.09% |
| 131 | MNKD MannKind Corp | 0.08% |
| 132 | GHRS GH Research PLC | 0.08% |
| 133 | OMER Omeros Corp | 0.08% |
| 134 | INBX Inhibrx Biosciences Inc | 0.08% |
| 135 | RAPP Rapport Therapeutics Inc | 0.08% |
| 136 | URGN UroGen Pharma Ltd | 0.08% |
| 137 | TYRA Tyra Biosciences Inc | 0.08% |
| 138 | CMPS Compass Pathways Plc | 0.08% |
| 139 | AMPH Amphastar Pharmaceuticals Inc | 0.08% |
| 140 | VOR Vor BioPharma Inc | 0.08% |
| 141 | ZLAB Zai Lab Ltd | 0.07% |
| 142 | MRVI Maravai LifeSciences Holdings Inc | 0.07% |
| 143 | HROW Harrow Inc | 0.07% |
| 144 | GRFS Grifols SA | 0.07% |
| 145 | CSTL Castle Biosciences Inc | 0.07% |
| 146 | SVRA Savara Inc | 0.07% |
| 147 | CRVS Corvus Pharmaceuticals Inc | 0.06% |
| 148 | SLN Silence Therapeutics PLC | 0.06% |
| 149 | ORIC ORIC Pharmaceuticals Inc | 0.06% |
| 150 | MGTX MeiraGTx Holdings plc | 0.06% |
| 151 | GLUE Monte Rosa Therapeutics Inc | 0.06% |
| 152 | SNDX Syndax Pharmaceuticals Inc | 0.05% |
| 153 | ALMS Alumis Inc | 0.05% |
| 154 | COLL Collegium Pharmaceutical Inc | 0.05% |
| 155 | SLDB Solid Biosciences Inc | 0.05% |
| 156 | RIGL Rigel Pharmaceuticals Inc | 0.05% |
| 157 | IRWD Ironwood Pharmaceuticals Inc | 0.05% |
| 158 | ANNX Annexon Inc | 0.05% |
| 159 | AURA Aura Biosciences Inc | 0.05% |
| 160 | ARDX Ardelyx Inc | 0.05% |
| 161 | PRME Prime Medicine Inc | 0.05% |
| 162 | ABUS Arbutus Biopharma Corp | 0.05% |
| 163 | JANX Janux Therapeutics Inc | 0.05% |
| 164 | OABI OmniAb Inc | 0.05% |
| 165 | PAHC Phibro Animal Health Corp | 0.05% |
| 166 | CGEM Cullinan Therapeutics Inc | 0.05% |
| 167 | MESO Mesoblast Ltd | 0.05% |
| 168 | FDMT 4D Molecular Therapeutics Inc | 0.04% |
| 169 | CADL Candel Therapeutics Inc | 0.04% |
| 170 | ZVRA Zevra Therapeutics Inc | 0.04% |
| 171 | SGMT Sagimet Biosciences Inc | 0.04% |
| 172 | OLMA Olema Pharmaceuticals Inc | 0.04% |
| 173 | BCAX Bicara Therapeutics Inc | 0.04% |
| 174 | KURA Kura Oncology Inc | 0.04% |
| 175 | SANA Sana Biotechnology Inc | 0.04% |
| 176 | DSGN Design Therapeutics Inc | 0.04% |
| 177 | WVE Wave Life Sciences Inc | 0.04% |
| 178 | AVBP ArriVent Biopharma Inc | 0.04% |
| 179 | GERN Geron Corp | 0.04% |
| 180 | PACB Pacific Biosciences of California Inc | 0.04% |
| 181 | ACRS Aclaris Therapeutics Inc | 0.04% |
| 182 | RGNX REGENXBIO Inc | 0.04% |
| 183 | NGNE Neurogene Inc | 0.03% |
| 184 | PHAT Phathom Pharmaceuticals Inc | 0.03% |
| 185 | GLPGF Lakefront Biotherapeutics NV | 0.03% |
| 186 | EOLS Evolus Inc | 0.03% |
| 187 | KMDA Kamada Ltd | 0.03% |
| 188 | CTMX CytomX Therapeutics Inc | 0.03% |
| 189 | TKNO Alpha Teknova Inc | 0.03% |
| 190 | AQST Aquestive Therapeutics Inc | 0.03% |
| 191 | ARVN Arvinas Inc | 0.03% |
| 192 | PRTA Prothena Corp PLC | 0.03% |
| 193 | PBYI Puma Biotechnology Inc | 0.03% |
| 194 | CRMD CorMedix Inc | 0.03% |
| 195 | TECX Tectonic Therapeutic Inc | 0.03% |
| 196 | LYEL Lyell Immunopharma Inc | 0.02% |
| 197 | SPRY ARS Pharmaceuticals Inc | 0.02% |
| 198 | ALT Altimmune Inc | 0.02% |
| 199 | EDIT Editas Medicine Inc | 0.02% |
| 200 | PEPG PepGen Inc | 0.02% |
| 201 | OBIO Orchestra BioMed Holdings Inc | 0.02% |
| 202 | CTNM Contineum Therapeutics Inc | 0.02% |
| 203 | CCCC C4 Therapeutics Inc | 0.02% |
| 204 | AVIR Atea Pharmaceuticals Inc | 0.02% |
| 205 | ENTA Enanta Pharmaceuticals Inc | 0.02% |
| 206 | KYTX Kyverna Therapeutics Inc | 0.02% |
| 207 | ALLO Allogene Therapeutics Inc | 0.02% |
| 208 | FULC Fulcrum Therapeutics Inc | 0.02% |
| 209 | LRMR Larimar Therapeutics Inc | 0.02% |
| 210 | BIOA BioAge Labs Inc | 0.02% |
| 211 | RCKT Rocket Pharmaceuticals Inc | 0.02% |
| 212 | ARCT Arcturus Therapeutics Holdings Inc | 0.02% |
| 213 | VNDA Vanda Pharmaceuticals Inc | 0.02% |
| 214 | LXEO Lexeo Therapeutics Inc | 0.02% |
| 215 | QSI Quantum-Si Inc | 0.02% |
| 216 | AUTL Autolus Therapeutics PLC | 0.02% |
| 217 | IMRX Immuneering Corp | 0.02% |
| 218 | LNDC Lifecore Biomedical Inc | 0.02% |
| 219 | CABA Cabaletta Bio Inc | 0.02% |
| 220 | ACIU AC Immune SA | 0.01% |
| 221 | SIGA SIGA Technologies Inc | 0.01% |
| 222 | TRDA Entrada Therapeutics Inc | 0.01% |
| 223 | KROS Keros Therapeutics Inc | 0.01% |
| 224 | ADGI Invivyd Inc | 0.01% |
| 225 | UPB Upstream Bio Inc | 0.01% |
| 226 | BCYC Bicycle Therapeutics PLC | 0.01% |
| 227 | SION Sionna Therapeutics Inc | 0.01% |
| 228 | HUMA Humacyte Inc | 0.01% |
| 229 | PYXS Pyxis Oncology Inc | 0.01% |
| 230 | MENS Jyong Biotech Ltd | 0.01% |
| 231 | LENZ LENZ Therapeutics Inc | 0.01% |
| 232 | FHTX Foghorn Therapeutics Inc | 0.01% |
| 233 | CDXS Codexis Inc | 0.01% |
| 234 | VYGR Voyager Therapeutics Inc | 0.01% |
| 235 | AVXL Anavex Life Sciences Corp | 0.01% |
| 236 | IMAB NovaBridge Biosciences | 0.01% |
| 237 | BDTX Black Diamond Therapeutics Inc | 0.01% |
| 238 | CHRS Coherus Oncology Inc | 0.01% |
| 239 | NMRA Neumora Therapeutics Inc | 0.01% |
| 240 | TNYA Tenaya Therapeutics Inc | 0.00% |
| 241 | GOSS Gossamer Bio Inc | 0.00% |
| 242 | RANI Rani Therapeutics Holdings Inc | 0.00% |
| 243 | CRBU Caribou Biosciences Inc | 0.00% |
| 244 | AARD Aardvark Therapeutics Inc | 0.00% |
| 245 | EYPT EyePoint Inc | 0.00% |
| 246 | IBBQ Cartesian Therapeutics Inc 12/31/2050 | 0.00% |
| 247 | THRD Third Harmonic Bio Inc | 0.00% |
Sector breakdown
Healthcare100.0%
Country breakdown
United States95.0%
United Kingdom2.1%
France1.0%
Canada0.5%
Netherlands0.4%
Denmark0.3%
Switzerland0.3%
Ireland0.1%
China0.1%
Spain0.1%
Australia0.0%
Israel0.0%
Distributions
| Date | Per unit |
|---|---|
| Sep 21, 2026 | $0.2304 |
| Jun 22, 2026 | $0.0342 |
| Mar 23, 2026 | $0.0361 |
| Dec 22, 2025 | $0.0906 |
| Sep 22, 2025 | $0.0958 |
| Jun 23, 2025 | $0.0287 |
| Mar 24, 2025 | $0.0402 |
| Dec 23, 2024 | $0.0619 |
| Sep 23, 2024 | $0.0894 |
| Jun 24, 2024 | $0.0506 |
| Mar 18, 2024 | $0.0435 |
| Dec 18, 2023 | $0.0526 |
| Sep 18, 2023 | $0.0412 |
| Jun 20, 2023 | $0.0453 |
| Mar 20, 2023 | $0.0378 |
| Dec 19, 2022 | $0.0419 |
| Sep 19, 2022 | $0.0377 |
| Jun 21, 2022 | $0.0426 |
| Mar 21, 2022 | $0.0378 |
| Dec 20, 2021 | $0.1051 |
| Sep 20, 2021 | $0.0432 |
Members of Congress who disclosed this ETF
No member of Congress has disclosed a trade in IBBQ in the filings we hold.
Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error