IBB iShares Biotechnology ETF
Issuer
IShares
Inception
Feb 5, 2001
AUM
$11.1B
Expense ratio
0.44%
Yield
0.16%
Asset class
Equity
Holdings
243
Last price
$213.43
The iShares Biotechnology ETF (IBB) is designed to mirror the investment performance of a specific market index. This index comprises publicly traded stocks from companies operating within the U.S. biotechnology sector.
+29.4%
2025-11-13low 160.41 · high 221.132026-11-13
Performance
| 1M | 3M | YTD | 1Y | 3Y ann. | 5Y ann. | |
|---|---|---|---|---|---|---|
| IBB | +6.7% | +7.3% | +26.5% | +30.7% | +22.7% | +6.9% |
| Equity average (4613 funds) | -2.1% | +2.7% | +87.8% | +61353.1% | +13.9% | +2.4% |
Insider activity in the holdings
Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$1.0M net.
| Holding | Weight | Insiders bought | Insiders sold |
|---|---|---|---|
| KOD KODIAK SCIENCES | 0.43% | $181.3M | $2.7M |
| LYEL LYELL IMMUNOPHARMA | 0.01% | $50.0M | $216K |
| MDGL MADRIGAL PHARMACEUTICALS | 0.63% | $35.0M | $7.0M |
| RAPP RAPPORT THERAPEUTICS | 0.05% | $22.0M | $4.5M |
| SRRK SCHOLAR ROCK HOLDING | 0.31% | $12.0M | $0 |
| ALMS ALUMIS | 0.04% | $10.7M | $1.0M |
| PRTA PROTHENA PLC | 0.03% | $9.8M | $0 |
| INBX INHIBRX BIOSCIENCES INC | 0.07% | $6.3M | $279K |
| KURA KURA ONCOLOGY | 0.05% | $2.4M | $1.7M |
| XENE XENON PHARMACEUTICALS | 0.26% | $1.7M | $426K |
| ABCL ABCELLERA BIOLOGICS | 0.20% | $1.4M | $0 |
| RGNX REGENXBIO | 0.04% | $949K | $0 |
| STVN STEVANATO GROUP | 0.05% | $601K | $293K |
| ALNY ALNYLAM PHARMACEUTICALS | 1.44% | $543K | $399K |
| LRMR LARIMAR THERAPEUTICS | 0.01% | $382K | $0 |
Holdings · as of Nov 12, 2026
| # | Holding | Weight |
|---|---|---|
| 1 | GILD GILEAD SCIENCES | 8.87% |
| 2 | AMGN AMGEN INC | 8.32% |
| 3 | VRTX VERTEX PHARMACEUTICALS | 7.68% |
| 4 | REGN REGENERON PHARMACEUTICALS | 6.43% |
| 5 | MRNA MODERNA | 6.15% |
| 6 | ARGX ARGENX SE ADR | 3.67% |
| 7 | NTRA NATERA | 2.91% |
| 8 | BIIB BIOGEN | 2.51% |
| 9 | ONC BEONE MEDICINES AG | 2.39% |
| 10 | RVMD REVOLUTION MEDICINES | 2.36% |
| 11 | ILMN ILLUMINA INC | 2.17% |
| 12 | GMAB GENMAB SPONSORED ADR | 2.02% |
| 13 | INSM INSMED | 1.76% |
| 14 | UTHR UNITED THERAPEUTICS | 1.67% |
| 15 | INCY INCYTE CORP | 1.66% |
| 16 | ROIV ROIVANT SCIENCES LTD | 1.48% |
| 17 | ALNY ALNYLAM PHARMACEUTICALS | 1.44% |
| 18 | NBIX NEUROCRINE BIOSCIENCES | 1.19% |
| 19 | EXEL EXELIXIS INC | 1.15% |
| 20 | CRL CHARLES RIVER LABORATORIES INTERNA | 1.09% |
| 21 | ASND ASCENDIS PHARMA | 1.08% |
| 22 | MEDP MEDPACE HOLDINGS | 1.01% |
| 23 | BBIO BRIDGEBIO PHARMA | 0.94% |
| 24 | HALO HALOZYME THERAPEUTICS | 0.77% |
| 25 | TECH BIO TECHNE | 0.77% |
| 26 | BMRN BIOMARIN PHARMACEUTICAL | 0.75% |
| 27 | RGEN REPLIGEN | 0.70% |
| 28 | KYMR KYMERA THERAPEUTICS | 0.68% |
| 29 | PCVX VAXCYTE | 0.67% |
| 30 | MDGL MADRIGAL PHARMACEUTICALS | 0.63% |
| 31 | PRAX PRAXIS PRECISION MEDICINES | 0.62% |
| 32 | TEM TEMPUS AI CLASS A | 0.58% |
| 33 | SYRE SPYRE THERAPEUTICS INC | 0.57% |
| 34 | BNTX BIONTECH SE ADR | 0.57% |
| 35 | PTGX PROTAGONIST THERAPEUTICS | 0.56% |
| 36 | KRYS KRYSTAL BIOTECH | 0.54% |
| 37 | TWST TWIST BIOSCIENCE | 0.53% |
| 38 | CYTK CYTOKINETICS | 0.53% |
| 39 | ALKS ALKERMES | 0.53% |
| 40 | RYTM RHYTHM PHARMACEUTICALS | 0.50% |
| 41 | TXG 10X GENOMICS CLASS A | 0.49% |
| 42 | BRKR BRUKER | 0.47% |
| 43 | ABVX ABIVAX AMERICAN DEPOSITARY SHARES | 0.45% |
| 44 | AXSM AXSOME THERAPEUTICS | 0.44% |
| 45 | ARWR ARROWHEAD PHARMACEUTICALS | 0.44% |
| 46 | KOD KODIAK SCIENCES | 0.43% |
| 47 | ORKA ORUKA THERAPEUTICS | 0.43% |
| 48 | GRAL GRAIL INC | 0.36% |
| 49 | PTCT PTC THERAPEUTICS | 0.35% |
| 50 | MIRM MIRUM PHARMACEUTICALS | 0.34% |
| 51 | TVTX TRAVERE THERAPEUTICS | 0.32% |
| 52 | ADPT ADAPTIVE BIOTECHNOLOGIES | 0.31% |
| 53 | SRRK SCHOLAR ROCK HOLDING | 0.31% |
| 54 | IONS IONIS PHARMACEUTICALS | 0.31% |
| 55 | COGT COGENT BIOSCIENCES | 0.31% |
| 56 | DFTX DEFINIUM THERAPEUTICS INC | 0.30% |
| 57 | CGON CG ONCOLOGY | 0.29% |
| 58 | ERAS ERASCA | 0.28% |
| 59 | CRSP CRISPR THERAPEUTICS AG | 0.28% |
| 60 | EWTX EDGEWISE THERAPEUTICS | 0.26% |
| 61 | XENE XENON PHARMACEUTICALS | 0.26% |
| 62 | CDNA CAREDX | 0.26% |
| 63 | TNGX TANGO THERAPEUTICS | 0.24% |
| 64 | TARS TARSUS PHARMACEUTICALS | 0.24% |
| 65 | AMLX AMYLYX PHARMACEUTICALS | 0.23% |
| 66 | RLAY RELAY THERAPEUTICS | 0.23% |
| 67 | LEGN LEGEND BIOTECH ADR REP | 0.22% |
| 68 | IOVA IOVANCE BIOTHERAPEUTICS INC | 0.22% |
| 69 | IMVT IMMUNOVANT | 0.21% |
| 70 | ACAD ACADIA PHARMACEUTICALS | 0.21% |
| 71 | CAI CARIS LIFE SCIENCES | 0.21% |
| 72 | ARQT ARCUTIS BIOTHERAPEUTICS | 0.21% |
| 73 | ELVN ENLIVEN THERAPEUTICS | 0.21% |
| 74 | VCEL VERICEL | 0.20% |
| 75 | IDYA IDEAYA BIOSCIENCES | 0.20% |
| 76 | ABCL ABCELLERA BIOLOGICS | 0.20% |
| 77 | DNLI DENALI THERAPEUTICS | 0.20% |
| 78 | ADMA ADMA BIOLOGICS | 0.19% |
| 79 | XNCR XENCOR | 0.19% |
| 80 | DYN DYNE THERAPEUTICS | 0.19% |
| 81 | IBRX IMMUNITYBIO | 0.18% |
| 82 | SMMT SUMMIT THERAPEUTICS | 0.17% |
| 83 | ZLAB ZAI LABORATORY ADR REPRESENTING LT | 0.17% |
| 84 | IRON DISC MEDICINE | 0.17% |
| 85 | BEAM BEAM THERAPEUTICS | 0.16% |
| 86 | GRFS GRIFOLS ADR REPRESENTING ONE NON-V | 0.14% |
| 87 | ZYME ZYMEWORKS | 0.14% |
| 88 | VCYT VERACYTE | 0.13% |
| 89 | BHVN BIOHAVEN | 0.13% |
| 90 | RXRX RECURSION PHARMACEUTICALS CLASS A | 0.13% |
| 91 | FTRE FORTREA HOLDINGS INC | 0.13% |
| 92 | AGIO AGIOS PHARMACEUTICALS | 0.13% |
| 93 | AUPH AURINIA PHARMACEUTICALS | 0.13% |
| 94 | REPL REPLIMUNE GROUP | 0.13% |
| 95 | VERA VERA THERAPEUTICS CLASS A | 0.12% |
| 96 | MBX MBX BIOSCIENCES | 0.12% |
| 97 | VIR VIR BIOTECHNOLOGY | 0.12% |
| 98 | SRPT SAREPTA THERAPEUTICS | 0.11% |
| 99 | BCRX BIOCRYST PHARMACEUTICALS | 0.11% |
| 100 | NRIX NURIX THERAPEUTICS | 0.11% |
| 101 | NAMS NEWAMSTERDAM PHARMA | 0.11% |
| 102 | RCUS ARCUS BIOSCIENCES | 0.11% |
| 103 | QURE UNIQURE | 0.11% |
| 104 | NVAX NOVAVAX | 0.11% |
| 105 | NTLA INTELLIA THERAPEUTICS | 0.10% |
| 106 | RARE ULTRAGENYX PHARMACEUTICAL | 0.10% |
| 107 | ABSI ABSCI CORP | 0.10% |
| 108 | STOK STOKE THERAPEUTICS | 0.10% |
| 109 | IBB BLK CSH FND TREASURY SL AGENCY | 0.10% |
| 110 | LKFT LAKEFRONT BIOTHERAPEUTICS ADR NV | 0.10% |
| 111 | IMCR IMMUNOCORE HOLDINGS ADR PLC | 0.10% |
| 112 | TRVI TREVI THERAPEUTICS | 0.10% |
| 113 | SEPN SEPTERNA | 0.10% |
| 114 | ANAB ANAPTYSBIO | 0.09% |
| 115 | GPCR STRUCTURE THERAPEUTICS ADR | 0.09% |
| 116 | MNKD MANNKIND | 0.09% |
| 117 | MAZE MAZE THERAPEUTICS | 0.09% |
| 118 | NVCR NOVOCURE | 0.09% |
| 119 | PSNL PERSONALIS | 0.08% |
| 120 | TSHA TAYSHA GENE THERAPIES | 0.08% |
| 121 | PHVS PHARVARIS N V | 0.08% |
| 122 | TYRA TYRA BIOSCIENCES | 0.07% |
| 123 | ANRO ALTO NEUROSCIENCE | 0.07% |
| 124 | URGN UROGEN PHARMA | 0.07% |
| 125 | NUVB NUVATION BIO CLASS A | 0.07% |
| 126 | CMPS COMPASS PATHWAYS ADR PLC | 0.07% |
| 127 | CSTL CASTLE BIOSCIENCES | 0.07% |
| 128 | MESO MESOBLAST ADR REPRESENTING | 0.07% |
| 129 | INBX INHIBRX BIOSCIENCES INC | 0.07% |
| 130 | ZBIO ZENAS BIOPHARMA | 0.07% |
| 131 | MLYS MINERALYS THERAPEUTICS | 0.07% |
| 132 | GHRS GH RESEARCH PLC | 0.07% |
| 133 | ALVO ALVOTECH SA | 0.06% |
| 134 | MRVI MARAVAI LIFESCIENCES HOLDINGS CLAS | 0.06% |
| 135 | RIGL RIGEL PHARMACEUTICALS | 0.05% |
| 136 | IRWD IRONWOOD PHARMA CLASS A | 0.05% |
| 137 | SNDX SYNDAX PHARMACEUTICALS | 0.05% |
| 138 | RAPP RAPPORT THERAPEUTICS | 0.05% |
| 139 | PGEN PRECIGEN | 0.05% |
| 140 | SLN SILENCE THERAPEUTICS ADR REPRESENT | 0.05% |
| 141 | CRVS CORVUS PHARMACEUTICALS | 0.05% |
| 142 | JANX JANUX THERAPEUTICS | 0.05% |
| 143 | MGTX MEIRAGTX HOLDINGS PLC | 0.05% |
| 144 | STVN STEVANATO GROUP | 0.05% |
| 145 | ZVRA ZEVRA THERAPEUTICS | 0.05% |
| 146 | CTKB CYTEK BIOSCIENCES | 0.05% |
| 147 | ANNX ANNEXON | 0.05% |
| 148 | KURA KURA ONCOLOGY | 0.05% |
| 149 | SGMT SAGIMET BIOSCIENCES SERIES A | 0.04% |
| 150 | SLDB SOLID BIOSCIENCES INC | 0.04% |
| 151 | FDMT 4D MOLECULAR THERAPEUTICS INC | 0.04% |
| 152 | GERN GERON | 0.04% |
| 153 | ALMS ALUMIS | 0.04% |
| 154 | OPK OPKO HEALTH | 0.04% |
| 155 | ABUS ARBUTUS BIOPHARMA | 0.04% |
| 156 | ORIC ORIC PHARMACEUTICALS | 0.04% |
| 157 | OABI OMNIAB INC | 0.04% |
| 158 | GLUE MONTE ROSA THERAPEUTICS | 0.04% |
| 159 | PACB PACIFIC BIOSCIENCES OF CALIFORNIA | 0.04% |
| 160 | OLMA OLEMA PHARMACEUTICALS | 0.04% |
| 161 | CADL CANDEL THERAPEUTICS INC | 0.04% |
| 162 | WVE WAVE LIFE SCIENCES | 0.04% |
| 163 | CGEM CULLINAN THERAPEUTICS | 0.04% |
| 164 | RGNX REGENXBIO | 0.04% |
| 165 | SVRA SAVARA | 0.03% |
| 166 | AURA AURA BIOSCIENCES | 0.03% |
| 167 | MYGN MYRIAD GENETICS | 0.03% |
| 168 | DNA GINKGO BIOWORKS HOLDINGS CLASS A | 0.03% |
| 169 | ACRS ACLARIS THERAPEUTICS | 0.03% |
| 170 | AVBP ARRIVENT BIOPHARMA | 0.03% |
| 171 | BCAX BICARA THERAPEUTICS INC | 0.03% |
| 172 | FLGT FULGENT GENETICS | 0.03% |
| 173 | SANA SANA BIOTECHNOLOGY | 0.03% |
| 174 | PRME PRIME MEDICINE | 0.03% |
| 175 | CTMX CYTOMX THERAPEUTICS | 0.03% |
| 176 | ARVN ARVINAS | 0.03% |
| 177 | NGNE NEUROGENE | 0.03% |
| 178 | PRTA PROTHENA PLC | 0.03% |
| 179 | DSGN DESIGN THERAPEUTICS | 0.03% |
| 180 | ALT ALTIMMUNE | 0.02% |
| 181 | PEPG PEPGEN | 0.02% |
| 182 | EDIT EDITAS MEDICINE | 0.02% |
| 183 | CCCC C4 THERAPEUTICS | 0.02% |
| 184 | CTNM CONTINEUM THERAPEUTICS CLASS A | 0.02% |
| 185 | PHAT PHATHOM PHARMACEUTICALS | 0.02% |
| 186 | ENTA ENANTA PHARMACEUTICALS INC | 0.02% |
| 187 | EBS EMERGENT BIOSOLUTIONS | 0.02% |
| 188 | FULC FULCRUM THERAPEUTICS | 0.02% |
| 189 | AVIR ATEA PHARMACEUTICALS | 0.02% |
| 190 | RCKT ROCKET PHARMACEUTICALS | 0.02% |
| 191 | SPRY ARS PHARMACEUTICALS | 0.02% |
| 192 | LAB STANDARD BIOTOOLS | 0.02% |
| 193 | ARCT ARCTURUS THERAPEUTICS HOLDINGS INC | 0.02% |
| 194 | VNDA VANDA PHARMACEUTICALS INC | 0.02% |
| 195 | IMRX IMMUNEERING CLASS A | 0.01% |
| 196 | QSI QUANTUM SI INC CLASS A | 0.01% |
| 197 | ALLO ALLOGENE THERAPEUTICS | 0.01% |
| 198 | CABA CABALETTA BIO | 0.01% |
| 199 | LXEO LEXEO THERAPEUTICS | 0.01% |
| 200 | AUTL AUTOLUS THERAPEUTICS ADR PLC | 0.01% |
| 201 | LCTX LINEAGE CELL THERAPEUTICS INC | 0.01% |
| 202 | TECX TECTONIC THERAPEUTIC | 0.01% |
| 203 | KYTX KYVERNA THERAPEUTICS | 0.01% |
| 204 | BIOA BIOAGE LABS | 0.01% |
| 205 | KROS KEROS THERAPEUTICS | 0.01% |
| 206 | ADCT ADC THERAPEUTICS LTD | 0.01% |
| 207 | HUMA HUMACYTE INC | 0.01% |
| 208 | ACIU AC IMMUNE SA AG | 0.01% |
| 209 | BCYC BICYCLE THERAPEUTICS ADR PLC | 0.01% |
| 210 | LRMR LARIMAR THERAPEUTICS | 0.01% |
| 211 | TRDA ENTRADA THERAPEUTICS | 0.01% |
| 212 | LYEL LYELL IMMUNOPHARMA | 0.01% |
| 213 | BBOT BRIDGEBIO ONCOLOGY THERAPEUTICS IN | 0.01% |
| 214 | QTRX QUANTERIX | 0.01% |
| 215 | UPB UPSTREAM BIO | 0.01% |
| 216 | LENZ LENZ THERAPEUTICS | 0.01% |
| 217 | PYXS PYXIS ONCOLOGY INC | 0.01% |
| 218 | CDXS CODEXIS | 0.01% |
| 219 | SION SIONNA THERAPEUTICS | 0.01% |
| 220 | AVXL ANAVEX LIFE SCIENCES CORP | 0.01% |
| 221 | TKNO ALPHA TEKNOVA | 0.01% |
| 222 | VYGR VOYAGER THERAPEUTICS | 0.01% |
| 223 | BDTX BLACK DIAMOND THERAPEUTICS INC | 0.01% |
| 224 | TNYA TENAYA THERAPEUTICS | 0.01% |
| 225 | CATX PERSPECTIVE THERAPEUTICS | 0.01% |
| 226 | NBP NOVABRIDGE BIOSCIENCES ADR | 0.00% |
| 227 | FHTX FOGHORN THERAPEUTICS | 0.00% |
| 228 | GOSS GOSSAMER BIO | 0.00% |
| 229 | MENS JYONG BIOTECH LTD | 0.00% |
| 230 | CLLS CELLECTIS ADR REPRESENTING SA | 0.00% |
| 231 | NMRA NEUMORA THERAPEUTICS INC | 0.00% |
| 232 | CRBU CARIBOU BIOSCIENCES | 0.00% |
| 233 | AARD AARDVARK THERAPEUTICS | 0.00% |
| 234 | IMMP IMMUTEP ADS REPRESENTING LTD | 0.00% |
| 235 | THRD THIRD HARMONIC BIO INC | 0.00% |
Sector breakdown
Healthcare100.0%
Country breakdown
United States94.3%
Denmark2.1%
United Kingdom1.6%
Canada0.5%
France0.4%
Switzerland0.3%
Netherlands0.3%
China0.2%
Spain0.1%
Ireland0.1%
Australia0.1%
Italy0.1%
Distributions
| Date | Per unit |
|---|---|
| Sep 15, 2026 | $0.0112 |
| Jun 15, 2026 | $0.0238 |
| Mar 17, 2026 | $0.1218 |
| Dec 16, 2025 | $0.1831 |
| Sep 16, 2025 | $0.0828 |
| Mar 18, 2025 | $0.1212 |
| Dec 17, 2024 | $0.0624 |
| Sep 25, 2024 | $0.2005 |
| Mar 21, 2024 | $0.1260 |
| Dec 20, 2023 | $0.1240 |
| Sep 26, 2023 | $0.1532 |
| Jun 7, 2023 | $0.0062 |
| Mar 23, 2023 | $0.0646 |
| Dec 13, 2022 | $0.1010 |
| Sep 26, 2022 | $0.1590 |
| Jun 9, 2022 | $0.0310 |
| Mar 24, 2022 | $0.1180 |
| Dec 13, 2021 | $0.0410 |
| Sep 24, 2021 | $0.1240 |
| Jun 10, 2021 | $0.0232 |
| Mar 25, 2021 | $0.1310 |
| Dec 14, 2020 | $0.0650 |
| Sep 23, 2020 | $0.0630 |
| Jun 15, 2020 | $0.1270 |
| Mar 25, 2020 | $0.0550 |
| Dec 30, 2019 | $0.0630 |
| Dec 16, 2019 | $0.0580 |
| Sep 24, 2019 | $0.0710 |
| Jun 17, 2019 | $0.0800 |
| Mar 20, 2019 | $0.1270 |
| Sep 26, 2018 | $0.0320 |
| Jun 26, 2018 | $0.1561 |
| Dec 21, 2017 | $0.1250 |
| Sep 26, 2017 | $0.0397 |
| Jun 27, 2017 | $0.0589 |
| Mar 24, 2017 | $0.0997 |
| Dec 22, 2016 | $0.0307 |
| Sep 26, 2016 | $0.0287 |
| Jun 21, 2016 | $0.0541 |
| Mar 23, 2016 | $0.0509 |
Members of Congress who disclosed this ETF
No member of Congress has disclosed a trade in IBB in the filings we hold.
Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error