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BBC Virtus Biotech Clinical Trials ETF

Issuer
Virtus
Inception
Dec 16, 2014
AUM
$31.6M
Expense ratio
0.65%
Yield
1.51%
Asset class
Sector Equity
Holdings
198
Last price
$43.49

This exchange-traded fund (ETF) endeavors to match the capital appreciation and income generation of the LifeSci Biotechnology Clinical Trials Index, disregarding fees and expenses. The underlying index focuses on tracking the financial progress of a carefully chosen group of biotechnology firms engaged in clinical trials. It is important to note that, as of February 27, the fund's official name transitioned from Virtus LifeSci Biotech Clinical Trials ETF to Virtus Biotech Clinical Trials ETF.

+34.9%
2025-11-13low 31.46 · high 56.032026-11-13

Performance

1M3MYTD1Y3Y ann.5Y ann.
BBC+7.0%-16.9%+12.8%+38.2%+35.7%-0.4%
Sector Equity average (79 funds)-1.3%-4.1%+12.7%+14.3%+15.8%+5.2%

Insider activity in the holdings

Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$4.6M net.

HoldingWeightInsiders boughtInsiders sold
KOD Kodiak Sciences Inc2.37%$181.3M$2.7M
RAPP Rapport Therapeutics Inc0.52%$22.0M$4.5M
SRRK Scholar Rock Holding Corp0.78%$12.0M$0
ALMS Alumis Inc0.20%$10.7M$1.0M
PRTA Prothena Corp PLC0.78%$9.8M$0
IMTX Immatics NV0.53%$7.5M$0
INBX Inhibrx Biosciences Inc0.73%$6.3M$279K
XENE Xenon Pharmaceuticals Inc0.60%$1.7M$426K
RLMD Relmada Therapeutics Inc0.49%$1.7M$0
ABCL AbCellera Biologics Inc1.69%$1.4M$0
RGNX REGENXBIO Inc0.94%$949K$0
DMRA Damora Therapeutics Inc0.83%$253K$0
NAMS Newamsterdam Pharma Co NV0.50%$227K$4.7M
ANNX Annexon Inc0.66%$100K$0
EYPT EyePoint Inc0.02%$52K$0

Holdings · as of Nov 13, 2026

#HoldingWeight
1XNCR Xencor Inc2.40%
2KOD Kodiak Sciences Inc2.37%
3TRAX First Tracks Biotherapeutics Inc2.12%
4REPL Replimune Group Inc1.81%
5ABCL AbCellera Biologics Inc1.69%
6AMLX Amylyx Pharmaceuticals Inc1.61%
7VRDN Viridian Therapeutics Inc1.41%
8SGP SpyGlass Pharma Inc1.40%
9MANE VeraDermics Inc1.20%
10MBX MBX Biosciences Inc1.20%
11LBRX LB Pharmaceuticals Inc1.16%
12KYMR Kymera Therapeutics Inc1.16%
13PRME Prime Medicine Inc1.15%
14ORKA Oruka Therapeutics Inc1.13%
15MAZE Maze Therapeutics Inc1.13%
16VIR Vir Biotechnology Inc1.13%
17PVLA Palvella Therapeutics Inc1.11%
18FDMT 4D Molecular Therapeutics Inc1.09%
19ANRO Alto Neuroscience Inc1.07%
20ZBIO Zenas Biopharma Inc1.07%
21PCVX Vaxcyte Inc1.07%
22VOR Vor BioPharma Inc1.03%
23DFTX Definium Therapeutics Inc1.03%
24EWTX Edgewise Therapeutics Inc1.01%
25SEPN Septerna Inc1.00%
26BHVN Biohaven Ltd1.00%
27RLAY Relay Therapeutics Inc0.98%
28SYRE Spyre Therapeutics Inc0.98%
29PRAX Praxis Precision Medicines Inc0.96%
30IRON Disc Medicine Inc0.95%
31RGNX REGENXBIO Inc0.94%
32CGON CG Oncology Inc0.90%
33MNPR Monopar Therapeutics Inc0.89%
34ERAS Erasca Inc0.88%
35SMMT Summit Therapeutics Inc0.88%
36AURA Aura Biosciences Inc0.88%
37RVMD Revolution Medicines Inc0.87%
38QUIT Achieve Life Sciences Inc0.86%
39RXRX Recursion Pharmaceuticals Inc0.84%
40IDYA Ideaya Biosciences Inc0.83%
41BLTE Belite Bio Inc0.83%
42DMRA Damora Therapeutics Inc0.83%
43PHVS Pharvaris NV0.82%
44ELVN Enliven Therapeutics Inc0.82%
45IMVT Immunovant Inc0.81%
46GENB Generate Biomedicines Inc0.81%
47ORIC ORIC Pharmaceuticals Inc0.80%
48DNTH Dianthus Therapeutics Inc0.80%
49JBIO Jade Biosciences Inc0.80%
50CADL Candel Therapeutics Inc0.80%
51SLS SELLAS Life Sciences Group Inc0.79%
52CLYM Climb Bio Inc0.79%
53SLDB Solid Biosciences Inc0.79%
54PRTA Prothena Corp PLC0.78%
55SRRK Scholar Rock Holding Corp0.78%
56ANL Adlai Nortye Group Ltd0.78%
57IMNM Immunome Inc0.77%
58IMMX Immix Biopharma Inc0.76%
59RZLT Rezolute Inc0.75%
60MGTX MeiraGTx Holdings plc0.75%
61VKTX Viking Therapeutics Inc0.73%
62DYN Dyne Therapeutics Inc0.73%
63INBX Inhibrx Biosciences Inc0.73%
64DSGN Design Therapeutics Inc0.73%
65ASMB Assembly Biosciences Inc0.72%
66LXRX Lexicon Pharmaceuticals Inc0.72%
67CLDX Celldex Therapeutics Inc0.71%
68NRIX Nurix Therapeutics Inc0.71%
69CRVS Corvus Pharmaceuticals Inc0.71%
70SVRA Savara Inc0.70%
71NTLA Intellia Therapeutics Inc0.70%
72STOK Stoke Therapeutics Inc0.69%
73JANX Janux Therapeutics Inc0.68%
74ARVN Arvinas Inc0.67%
75GHRS GH Research PLC0.67%
76BCYC Bicycle Therapeutics PLC0.67%
77ABUS Arbutus Biopharma Corp0.67%
78RCKT Rocket Pharmaceuticals Inc0.67%
79QURE uniQure NV0.66%
80ANNX Annexon Inc0.66%
81VERA Vera Therapeutics Inc0.66%
82BEAM Beam Therapeutics Inc0.66%
83COGT Cogent Biosciences Inc0.66%
84ANAB AnaptysBio Inc0.64%
85NGNE Neurogene Inc0.64%
86SANA Sana Biotechnology Inc0.63%
87TNGX Tango Therapeutics Inc0.61%
88CGEM Cullinan Therapeutics Inc0.61%
89CBIO Crescent Biopharma Inc0.61%
90OLMA Olema Pharmaceuticals Inc0.60%
91XENE Xenon Pharmaceuticals Inc0.60%
92RCUS Arcus Biosciences Inc0.58%
93IVVD Invivyd Inc0.58%
94AKTS Aktis Oncology Inc0.57%
95TYRA Tyra Biosciences Inc0.57%
96CMPS Compass Pathways Plc0.57%
97TSHA Taysha Gene Therapies Inc0.55%
98ALT Altimmune Inc0.55%
99CELC Celcuity Inc0.54%
100TECX Tectonic Therapeutic Inc0.54%
101MLTX MoonLake Immunotherapeutics0.53%
102IMTX Immatics NV0.53%
103CTMX CytomX Therapeutics Inc0.52%
104RAPP Rapport Therapeutics Inc0.52%
105LXEO Lexeo Therapeutics Inc0.52%
106PROK ProKidney Corp0.51%
107OCS Oculis Holding AG0.51%
108MLYS Mineralys Therapeutics Inc0.51%
109NAMS Newamsterdam Pharma Co NV0.50%
110RLMD Relmada Therapeutics Inc0.49%
111NKTR Nektar Therapeutics0.48%
112WVE Wave Life Sciences Inc0.43%
113AVTX Avalo Therapeutics Inc0.43%
114GLUE Monte Rosa Therapeutics Inc0.42%
115UPB Upstream Bio Inc0.39%
116GPCR Structure Therapeutics Inc0.36%
117BCAX Bicara Therapeutics Inc0.36%
118CABA Cabaletta Bio Inc0.36%
119ALLO Allogene Therapeutics Inc0.35%
120AVBP ArriVent Biopharma Inc0.33%
121CAPR Capricor Therapeutics Inc0.32%
122EVMN Evommune Inc0.32%
123CMPX Compass Therapeutics Inc0.30%
124BBOT BridgeBio Oncology Therapeutics Inc0.24%
125BIOA BioAge Labs Inc0.24%
126ALMS Alumis Inc0.20%
127MPLT MapLight Therapeutics Inc0.20%
128BBC Cash/Cash equivalents0.11%
129SION Sionna Therapeutics Inc0.08%
130EYPT EyePoint Inc0.02%

Sector breakdown

Healthcare100.0%

Country breakdown

United States90.7%
Canada2.3%
United Kingdom2.0%
Netherlands2.0%
Ireland1.4%
Switzerland1.0%
China0.6%

Distributions

DatePer unit
Dec 22, 2025$0.6554
Dec 20, 2024$0.2395
Dec 20, 2023$0.0823
Dec 20, 2017$0.2972
Dec 21, 2015$0.1470

Members of Congress who disclosed this ETF

No member of Congress has disclosed a trade in BBC in the filings we hold.

Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error

BBC: Virtus Biotech Clinical Trials ETF — Holdings, Performance and Insider Activity | InsiderBuying.com