BBC Virtus Biotech Clinical Trials ETF
This exchange-traded fund (ETF) endeavors to match the capital appreciation and income generation of the LifeSci Biotechnology Clinical Trials Index, disregarding fees and expenses. The underlying index focuses on tracking the financial progress of a carefully chosen group of biotechnology firms engaged in clinical trials. It is important to note that, as of February 27, the fund's official name transitioned from Virtus LifeSci Biotech Clinical Trials ETF to Virtus Biotech Clinical Trials ETF.
Performance
| 1M | 3M | YTD | 1Y | 3Y ann. | 5Y ann. | |
|---|---|---|---|---|---|---|
| BBC | +7.0% | -16.9% | +12.8% | +38.2% | +35.7% | -0.4% |
| Sector Equity average (79 funds) | -1.3% | -4.1% | +12.7% | +14.3% | +15.8% | +5.2% |
Insider activity in the holdings
Open-market insider buying across this fund’s holdings over 90 days, weighted by holding weight: +$4.6M net.
| Holding | Weight | Insiders bought | Insiders sold |
|---|---|---|---|
| KOD Kodiak Sciences Inc | 2.37% | $181.3M | $2.7M |
| RAPP Rapport Therapeutics Inc | 0.52% | $22.0M | $4.5M |
| SRRK Scholar Rock Holding Corp | 0.78% | $12.0M | $0 |
| ALMS Alumis Inc | 0.20% | $10.7M | $1.0M |
| PRTA Prothena Corp PLC | 0.78% | $9.8M | $0 |
| IMTX Immatics NV | 0.53% | $7.5M | $0 |
| INBX Inhibrx Biosciences Inc | 0.73% | $6.3M | $279K |
| XENE Xenon Pharmaceuticals Inc | 0.60% | $1.7M | $426K |
| RLMD Relmada Therapeutics Inc | 0.49% | $1.7M | $0 |
| ABCL AbCellera Biologics Inc | 1.69% | $1.4M | $0 |
| RGNX REGENXBIO Inc | 0.94% | $949K | $0 |
| DMRA Damora Therapeutics Inc | 0.83% | $253K | $0 |
| NAMS Newamsterdam Pharma Co NV | 0.50% | $227K | $4.7M |
| ANNX Annexon Inc | 0.66% | $100K | $0 |
| EYPT EyePoint Inc | 0.02% | $52K | $0 |
Holdings · as of Nov 13, 2026
| # | Holding | Weight |
|---|---|---|
| 1 | XNCR Xencor Inc | 2.40% |
| 2 | KOD Kodiak Sciences Inc | 2.37% |
| 3 | TRAX First Tracks Biotherapeutics Inc | 2.12% |
| 4 | REPL Replimune Group Inc | 1.81% |
| 5 | ABCL AbCellera Biologics Inc | 1.69% |
| 6 | AMLX Amylyx Pharmaceuticals Inc | 1.61% |
| 7 | VRDN Viridian Therapeutics Inc | 1.41% |
| 8 | SGP SpyGlass Pharma Inc | 1.40% |
| 9 | MANE VeraDermics Inc | 1.20% |
| 10 | MBX MBX Biosciences Inc | 1.20% |
| 11 | LBRX LB Pharmaceuticals Inc | 1.16% |
| 12 | KYMR Kymera Therapeutics Inc | 1.16% |
| 13 | PRME Prime Medicine Inc | 1.15% |
| 14 | ORKA Oruka Therapeutics Inc | 1.13% |
| 15 | MAZE Maze Therapeutics Inc | 1.13% |
| 16 | VIR Vir Biotechnology Inc | 1.13% |
| 17 | PVLA Palvella Therapeutics Inc | 1.11% |
| 18 | FDMT 4D Molecular Therapeutics Inc | 1.09% |
| 19 | ANRO Alto Neuroscience Inc | 1.07% |
| 20 | ZBIO Zenas Biopharma Inc | 1.07% |
| 21 | PCVX Vaxcyte Inc | 1.07% |
| 22 | VOR Vor BioPharma Inc | 1.03% |
| 23 | DFTX Definium Therapeutics Inc | 1.03% |
| 24 | EWTX Edgewise Therapeutics Inc | 1.01% |
| 25 | SEPN Septerna Inc | 1.00% |
| 26 | BHVN Biohaven Ltd | 1.00% |
| 27 | RLAY Relay Therapeutics Inc | 0.98% |
| 28 | SYRE Spyre Therapeutics Inc | 0.98% |
| 29 | PRAX Praxis Precision Medicines Inc | 0.96% |
| 30 | IRON Disc Medicine Inc | 0.95% |
| 31 | RGNX REGENXBIO Inc | 0.94% |
| 32 | CGON CG Oncology Inc | 0.90% |
| 33 | MNPR Monopar Therapeutics Inc | 0.89% |
| 34 | ERAS Erasca Inc | 0.88% |
| 35 | SMMT Summit Therapeutics Inc | 0.88% |
| 36 | AURA Aura Biosciences Inc | 0.88% |
| 37 | RVMD Revolution Medicines Inc | 0.87% |
| 38 | QUIT Achieve Life Sciences Inc | 0.86% |
| 39 | RXRX Recursion Pharmaceuticals Inc | 0.84% |
| 40 | IDYA Ideaya Biosciences Inc | 0.83% |
| 41 | BLTE Belite Bio Inc | 0.83% |
| 42 | DMRA Damora Therapeutics Inc | 0.83% |
| 43 | PHVS Pharvaris NV | 0.82% |
| 44 | ELVN Enliven Therapeutics Inc | 0.82% |
| 45 | IMVT Immunovant Inc | 0.81% |
| 46 | GENB Generate Biomedicines Inc | 0.81% |
| 47 | ORIC ORIC Pharmaceuticals Inc | 0.80% |
| 48 | DNTH Dianthus Therapeutics Inc | 0.80% |
| 49 | JBIO Jade Biosciences Inc | 0.80% |
| 50 | CADL Candel Therapeutics Inc | 0.80% |
| 51 | SLS SELLAS Life Sciences Group Inc | 0.79% |
| 52 | CLYM Climb Bio Inc | 0.79% |
| 53 | SLDB Solid Biosciences Inc | 0.79% |
| 54 | PRTA Prothena Corp PLC | 0.78% |
| 55 | SRRK Scholar Rock Holding Corp | 0.78% |
| 56 | ANL Adlai Nortye Group Ltd | 0.78% |
| 57 | IMNM Immunome Inc | 0.77% |
| 58 | IMMX Immix Biopharma Inc | 0.76% |
| 59 | RZLT Rezolute Inc | 0.75% |
| 60 | MGTX MeiraGTx Holdings plc | 0.75% |
| 61 | VKTX Viking Therapeutics Inc | 0.73% |
| 62 | DYN Dyne Therapeutics Inc | 0.73% |
| 63 | INBX Inhibrx Biosciences Inc | 0.73% |
| 64 | DSGN Design Therapeutics Inc | 0.73% |
| 65 | ASMB Assembly Biosciences Inc | 0.72% |
| 66 | LXRX Lexicon Pharmaceuticals Inc | 0.72% |
| 67 | CLDX Celldex Therapeutics Inc | 0.71% |
| 68 | NRIX Nurix Therapeutics Inc | 0.71% |
| 69 | CRVS Corvus Pharmaceuticals Inc | 0.71% |
| 70 | SVRA Savara Inc | 0.70% |
| 71 | NTLA Intellia Therapeutics Inc | 0.70% |
| 72 | STOK Stoke Therapeutics Inc | 0.69% |
| 73 | JANX Janux Therapeutics Inc | 0.68% |
| 74 | ARVN Arvinas Inc | 0.67% |
| 75 | GHRS GH Research PLC | 0.67% |
| 76 | BCYC Bicycle Therapeutics PLC | 0.67% |
| 77 | ABUS Arbutus Biopharma Corp | 0.67% |
| 78 | RCKT Rocket Pharmaceuticals Inc | 0.67% |
| 79 | QURE uniQure NV | 0.66% |
| 80 | ANNX Annexon Inc | 0.66% |
| 81 | VERA Vera Therapeutics Inc | 0.66% |
| 82 | BEAM Beam Therapeutics Inc | 0.66% |
| 83 | COGT Cogent Biosciences Inc | 0.66% |
| 84 | ANAB AnaptysBio Inc | 0.64% |
| 85 | NGNE Neurogene Inc | 0.64% |
| 86 | SANA Sana Biotechnology Inc | 0.63% |
| 87 | TNGX Tango Therapeutics Inc | 0.61% |
| 88 | CGEM Cullinan Therapeutics Inc | 0.61% |
| 89 | CBIO Crescent Biopharma Inc | 0.61% |
| 90 | OLMA Olema Pharmaceuticals Inc | 0.60% |
| 91 | XENE Xenon Pharmaceuticals Inc | 0.60% |
| 92 | RCUS Arcus Biosciences Inc | 0.58% |
| 93 | IVVD Invivyd Inc | 0.58% |
| 94 | AKTS Aktis Oncology Inc | 0.57% |
| 95 | TYRA Tyra Biosciences Inc | 0.57% |
| 96 | CMPS Compass Pathways Plc | 0.57% |
| 97 | TSHA Taysha Gene Therapies Inc | 0.55% |
| 98 | ALT Altimmune Inc | 0.55% |
| 99 | CELC Celcuity Inc | 0.54% |
| 100 | TECX Tectonic Therapeutic Inc | 0.54% |
| 101 | MLTX MoonLake Immunotherapeutics | 0.53% |
| 102 | IMTX Immatics NV | 0.53% |
| 103 | CTMX CytomX Therapeutics Inc | 0.52% |
| 104 | RAPP Rapport Therapeutics Inc | 0.52% |
| 105 | LXEO Lexeo Therapeutics Inc | 0.52% |
| 106 | PROK ProKidney Corp | 0.51% |
| 107 | OCS Oculis Holding AG | 0.51% |
| 108 | MLYS Mineralys Therapeutics Inc | 0.51% |
| 109 | NAMS Newamsterdam Pharma Co NV | 0.50% |
| 110 | RLMD Relmada Therapeutics Inc | 0.49% |
| 111 | NKTR Nektar Therapeutics | 0.48% |
| 112 | WVE Wave Life Sciences Inc | 0.43% |
| 113 | AVTX Avalo Therapeutics Inc | 0.43% |
| 114 | GLUE Monte Rosa Therapeutics Inc | 0.42% |
| 115 | UPB Upstream Bio Inc | 0.39% |
| 116 | GPCR Structure Therapeutics Inc | 0.36% |
| 117 | BCAX Bicara Therapeutics Inc | 0.36% |
| 118 | CABA Cabaletta Bio Inc | 0.36% |
| 119 | ALLO Allogene Therapeutics Inc | 0.35% |
| 120 | AVBP ArriVent Biopharma Inc | 0.33% |
| 121 | CAPR Capricor Therapeutics Inc | 0.32% |
| 122 | EVMN Evommune Inc | 0.32% |
| 123 | CMPX Compass Therapeutics Inc | 0.30% |
| 124 | BBOT BridgeBio Oncology Therapeutics Inc | 0.24% |
| 125 | BIOA BioAge Labs Inc | 0.24% |
| 126 | ALMS Alumis Inc | 0.20% |
| 127 | MPLT MapLight Therapeutics Inc | 0.20% |
| 128 | BBC Cash/Cash equivalents | 0.11% |
| 129 | SION Sionna Therapeutics Inc | 0.08% |
| 130 | EYPT EyePoint Inc | 0.02% |
Sector breakdown
Country breakdown
Distributions
| Date | Per unit |
|---|---|
| Dec 22, 2025 | $0.6554 |
| Dec 20, 2024 | $0.2395 |
| Dec 20, 2023 | $0.0823 |
| Dec 20, 2017 | $0.2972 |
| Dec 21, 2015 | $0.1470 |
Members of Congress who disclosed this ETF
No member of Congress has disclosed a trade in BBC in the filings we hold.
Fund facts, prices, performance and distributions: our market-data vendor. Holdings: the vendor and SEC Form N-PORT. Insider and Congress data: InsiderBuying. Last updated Nov 13, 2026. This is historical data, not investment advice. Report a data error
